Haemophilia A Dental Management — NDEB AFK MCQ

Instant feedback + full explanation. One question, done properly.

HardOral SurgeryHaemophilia A Dental ManagementNDEB AFK

In a patient with hemophilia A (factor VIII deficiency), which haemostatic measure is most important before dental extraction?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Factor VIII replacement therapy to achieve adequate factor levels (ideally >50%)

For patients with haemophilia A requiring dental extraction, factor VIII replacement to achieve factor levels of at least 50% (ideally >80% for surgical extractions) is essential. This is coordinated with the patient's haematologist. For mild haemophilia A, DDAVP (desmopressin) may raise factor VIII levels sufficiently. Adjunctive local measures include sutures, tranexamic acid mouthwash (5% for 7 days), gelatin sponge, and oxidised cellulose. Antifibrinolytics (tranexamic acid 25 mg/kg TDS) are important adjuncts.

Reference: Hoffbrand – Postgraduate Haematology, 7th ed., 2016