Drug-Induced Gingival Overgrowth — NDEB AFK MCQ

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ModeratePharmacologyDrug-Induced Gingival OvergrowthNDEB AFK

Which drug class is most commonly associated with drug-induced gingival overgrowth?

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Correct answer: E — Calcium channel blockers

Calcium channel blockers (particularly nifedipine, amlodipine, diltiazem) are the most commonly prescribed drug class associated with gingival overgrowth, with prevalence rates of 6-83% depending on the specific drug and study. The other two main drug classes causing this condition are anticonvulsants (phenytoin, 50% prevalence) and immunosuppressants (cyclosporine, 25-30%). Plaque is a major co-factor. Management includes drug substitution (if possible), meticulous oral hygiene, and gingivectomy if needed.

Reference: Newman – Newman and Carranza's Clinical Periodontology, 13th ed., 2019