Osteoradionecrosis — NDEB AFK MCQ

Instant feedback + full explanation. One question, done properly.

ModerateOral MedicineOsteoradionecrosisNDEB AFK

A 55-year-old male with a history of radiation therapy to the head and neck for nasopharyngeal carcinoma 2 years ago presents with exposed mandibular bone. What is this condition called?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Osteoradionecrosis (ORN)

Osteoradionecrosis (ORN) is the necrosis of irradiated bone (typically mandible) that fails to heal. It results from radiation-induced hypovascular, hypocellular, hypoxic tissue (Marx's 3H theory) that cannot mount an adequate wound healing response. The mandible is more commonly affected than the maxilla due to its denser bone and single blood supply (inferior alveolar artery). Prevention includes comprehensive dental treatment BEFORE radiation, fluoride trays, and avoidance of extractions post-radiation (or hyperbaric oxygen if extraction is required).

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016