Epinephrine Maximum Dose — NDEB AFK MCQ
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Correct answer: D — 200 μg
The maximum recommended dose of epinephrine for a healthy adult is 200 μg (0.2 mg). At 1:100,000 concentration (10 μg/mL per 1.7 mL cartridge = 17 μg), this allows approximately 11 cartridges. For medically compromised patients (cardiovascular disease, uncontrolled hyperthyroidism), a conservative maximum of 40 μg is often recommended (approximately 2 cartridges of 1:100,000). The cardiac dose (1:80,000 in gingival retraction cord) should also be factored into the total dose.
Reference: Malamed – Handbook of Local Anesthesia, 7th ed., 2020