Fluoride Probably Toxic Dose — NDEB AFK MCQ
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Correct answer: B — 5 mg/kg body weight
The probably toxic dose (PTD) of fluoride is 5 mg/kg body weight. At this dose, systemic toxicity is likely, and emergency treatment (induce vomiting if within 30 minutes, administer calcium-containing antacid or milk, transport to hospital) is required. The certainly lethal dose (CLD) is estimated at 32-64 mg/kg. Early signs of fluoride toxicity include nausea, vomiting, hypersalivation, abdominal pain, and diarrhoea.
Reference: Dean – McDonald and Avery's Dentistry for the Child and Adolescent, 11th ed., 2021