Sjögren Syndrome — NDEB AFK MCQ

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ModerateOral MedicineSjögren SyndromeNDEB AFK

A 40-year-old patient presents with bilateral, painless enlargement of the parotid glands. Blood work shows elevated ESR and positive anti-SSA (Ro) antibodies. Which condition is most likely?

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Correct answer: A — Sjögren syndrome

Bilateral painless parotid enlargement with positive anti-SSA/Ro antibodies and elevated ESR is characteristic of Sjögren syndrome (SS). SS is an autoimmune exocrinopathy affecting salivary and lacrimal glands. Diagnostic criteria (ACR/EULAR 2016) include labial salivary gland biopsy (focus score ≥1), anti-SSA/Ro positivity, ocular staining score, Schirmer test, and unstimulated salivary flow rate. Mumps is acute and unilateral initially.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016