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Hand-Foot-and-Mouth Disease — NDEB AFK MCQ

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ModerateOral PathologyHand-Foot-and-Mouth DiseaseNDEB AFK

Which virus causes hand-foot-and-mouth disease (HFMD) in children?

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Correct answer: D — Coxsackievirus A16

Hand-foot-and-mouth disease is caused primarily by Coxsackievirus A16 (and occasionally enterovirus 71). It presents with oral vesicles and shallow ulcers (especially anterior mouth), and maculopapular/vesicular lesions on the palms and soles. It is common in children under 5 years and is self-limiting. HSV-1 causes herpetic gingivostomatitis. HHV-6 causes roseola (exanthem subitum).

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016