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Erythroplakia — NDEB AFK MCQ

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ModerateOral PathologyErythroplakiaNDEB AFK

Which oral mucosal condition has the highest rate of malignant transformation?

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Correct answer: DErythroplakia

Erythroplakia has the highest rate of malignant transformation of all oral potentially malignant disorders, with over 50% of lesions showing severe dysplasia, carcinoma in situ, or invasive carcinoma at the time of biopsy. In contrast, the malignant transformation rate of leukoplakia is approximately 3-5% and oral lichen planus is approximately 1-2%. Erythroplakia appears as a velvety red patch that cannot be attributed to any other diagnosis.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016