Study Design for Prevention — NDEB AFK MCQ
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Correct answer: A — Randomised controlled trial (RCT)
A randomised controlled trial (RCT) is the gold standard study design for evaluating the efficacy of a preventive intervention (fluoride varnish). Random allocation to intervention and control groups minimises confounding and selection bias. The outcome (caries increment) can be compared between groups over a defined period. Blinding (examiner blinding) further reduces bias.
Reference: Burt & Eklund – Dentistry, Dental Practice, and the Community, 7th ed., 2005