IE Prophylaxis Indications — NDEB AFK MCQ
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Correct answer: B — Mitral valve prolapse with regurgitation
AHA 2021 guidelines recommend antibiotic prophylaxis only for patients at HIGHEST risk: (1) prosthetic heart valve or prosthetic material used for valve repair, (2) previous infective endocarditis, (3) unrepaired cyanotic congenital heart disease (including palliative shunts/conduits), (4) repaired CHD with prosthetic material within 6 months, (5) repaired CHD with residual defects, and (6) cardiac transplant with valvulopathy. Mitral valve prolapse (with or without regurgitation) no longer requires prophylaxis.
Reference: AHA – Prevention of Infective Endocarditis Guidelines, 2021