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IE Prophylaxis Regimen — NDEB AFK MCQ

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ModeratePharmacologyIE Prophylaxis RegimenNDEB AFK

A patient with a prosthetic heart valve requires extraction of two teeth. According to current CDA-endorsed guidelines (based on AHA 2021), what antibiotic prophylaxis regimen is recommended?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Amoxicillin 2 g orally 30-60 minutes before the procedure

Per AHA 2021 guidelines (endorsed by CDA), patients with prosthetic heart valves are in the highest-risk category for infective endocarditis and require antibiotic prophylaxis before dental procedures involving manipulation of gingival tissue, periapical regions, or oral mucosal perforation. The standard regimen is amoxicillin 2 g PO 30-60 minutes before the procedure. For penicillin-allergic patients: clindamycin 600 mg, azithromycin 500 mg, or cephalexin 2 g PO.

Reference: AHA – Prevention of Infective Endocarditis Guidelines, 2021; CDA Position Statement on IE