Aggressive Periodontitis — NDEB AFK MCQ

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ModeratePeriodontologyAggressive PeriodontitisNDEB AFK

Aggressive periodontitis (now classified as periodontitis Grade C, molar-incisor pattern) in an otherwise healthy adolescent is most commonly associated with which organism?

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Correct answer: D — Aggregatibacter actinomycetemcomitans

Aggregatibacter actinomycetemcomitans (Aa) is the organism most classically associated with the molar-incisor pattern of periodontitis in young patients (formerly called localized aggressive periodontitis). Aa produces leukotoxin (particularly the JP2 clone) which kills neutrophils, and it invades epithelial cells. Under the 2017 classification, this is now described as periodontitis, Grade C (rapid rate of progression), with a molar-incisor distribution.

Reference: Newman – Newman and Carranza's Clinical Periodontology, 13th ed., 2019