Guided Tissue Regeneration — NDEB AFK MCQ
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Correct answer: B — To prevent epithelial and connective tissue downgrowth into the defect
The GTR membrane acts as a physical barrier to prevent rapid downgrowth of epithelial cells and gingival connective tissue into the defect. This allows slower-proliferating cells (periodontal ligament cells, osteoblasts, cementoblasts) to repopulate the wound space and regenerate attachment apparatus. Membranes can be resorbable (collagen, polylactic acid) or non-resorbable (ePTFE, which requires second surgery for removal).
Reference: Newman – Newman and Carranza's Clinical Periodontology, 13th ed., 2019