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Adenomatoid Odontogenic Tumour — NDEB AFK MCQ

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HardOral PathologyAdenomatoid Odontogenic TumourNDEB AFK

A painless, well-circumscribed, slow-growing radiolucency in the anterior mandible of a 14-year-old has a histology showing nests of cuboidal epithelial cells forming duct-like structures and rosettes in an eosinophilic stroma. What is the most likely diagnosis?

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Correct answer: D — Adenomatoid odontogenic tumour

Adenomatoid odontogenic tumour (AOT) classically occurs in the anterior jaws of young females (<20 years) and is often associated with an impacted tooth (especially canines). Histologically, it shows duct-like structures (rosettes) lined by cuboidal to columnar epithelium within a spindle cell stroma. It is sometimes called 'two-thirds tumour' (2/3 in maxilla, anterior, and in females). It rarely recurs after conservative enucleation.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016