Oral Hairy Leukoplakia — NDEB AFK MCQ

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ModerateOral PathologyOral Hairy LeukoplakiaNDEB AFK

Which oral lesion is most strongly associated with Epstein-Barr virus (EBV) infection?

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Correct answer: E — Oral hairy leukoplakia

Oral hairy leukoplakia is caused by EBV replication in the superficial epithelium of the lateral tongue. It presents as white, corrugated, non-removable plaques that cannot be scraped off. It is strongly associated with immunosuppression (HIV/AIDS). Heck disease is caused by HPV-13/32. Verruca vulgaris and squamous papilloma are associated with HPV types 6, 11, or 2.

Reference: Neville – Oral and Maxillofacial Pathology, 4th ed., 2016