Collagen Biochemistry — NDEB AFK MCQ
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Correct answer: C — Hydroxyproline
Hydroxyproline is formed by post-translational hydroxylation of proline by prolyl hydroxylase (requiring vitamin C as a cofactor). It is virtually unique to collagen, and urinary hydroxyproline levels serve as a marker of collagen turnover and bone resorption. Glycine is present at every third position in collagen but is found in many other proteins.
Reference: Nanci – Ten Cate's Oral Histology, 9th ed., 2017