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Bone Resorption — NDEB AFK MCQ

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EasyBiomedical SciencesBone ResorptionNDEB AFK

Which cell type is responsible for bone resorption?

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Correct answer: COsteoclast

Osteoclasts are large multinucleated cells derived from the monocyte-macrophage lineage. They resorb bone by creating an acidic environment via hydrogen ion secretion (ruffled border) and releasing enzymes such as tartrate-resistant acid phosphatase (TRAP) and cathepsin K. Osteoblasts form bone; osteocytes are mature embedded osteoblasts.

Reference: Nanci – Ten Cate's Oral Histology, 9th ed., 2017