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ECT Safety in Pregnancy — MRCPsych Paper B MCQ

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HardPerinatal PsychiatryECT Safety in PregnancyMRCPsych Paper B

A 32-year-old woman at 31 weeks' gestation is admitted with severe psychotic depression. She has persistently refused food and fluids, is becoming dehydrated and remains at high risk of suicide. A rapid therapeutic response is required, and electroconvulsive therapy (ECT) is being considered. Which statement most accurately reflects current UK practice?

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Reveal the answer and explanation

Correct answer: EECT may be considered during pregnancy when severe illness creates serious maternal or fetal risk, following individualised specialist obstetric and anaesthetic assessment.

Explanation lettering: D = shown as A · C = shown as B · A = shown as C · E = shown as D · B = shown as E

B is correct. Pregnancy is not an absolute contraindication to ECT. NICE recommends considering it for severe depression, severe mixed affective states or mania, or catatonia when the woman's physical health or that of the fetus is at serious risk. Here, suicidality, dehydration and food refusal justify consideration of a treatment capable of producing a rapid response. ECT should follow individualised psychiatric, obstetric and anaesthetic assessment with appropriate pregnancy-specific precautions. Available safety evidence is limited mainly to case reports and series, so ECT should be described as relatively safe rather than risk-free. A overstates the risk in later pregnancy. C is wrong because serious maternal risk is independently sufficient. D incorrectly requires exhaustive medication failure despite urgency. E is wrong because severe, including psychotic, depression is a recognised indication during pregnancy.

Reference: National Institute for Health and Care Excellence. Antenatal and postnatal mental health: clinical management and service guidance (CG192), recommendation 1.8.22, 2014; last updated 2020 and supported by 2025 surveillance. https://www.nice.org.uk/guidance/cg192/chapter/Recommendations