Sugammadex 1:1 Molar Ratio — FRCA Primary MCQ
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Correct answer: E — 1:1
Sugammadex encapsulates rocuronium (or vecuronium) in a tight 1:1 molar ratio forming an inactive water-soluble complex. This complex is renally excreted. Because it is a 1:1 binding if insufficient sugammadex is given relative to the amount of NMB present recurarisation can occur.
Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care