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MAC Isoflurane 1.2% — FRCA Primary MCQ

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EasyPharmacology - Inhalational AgentsMAC Isoflurane 1.2%FRCA Primary

MAC of isoflurane in oxygen is:

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Correct answer: B1.2%

MAC values in O2: halothane 0.75% / isoflurane 1.2% / sevoflurane 2.0% / desflurane 6.0% / N2O 104%. These are measured in healthy 30-40 year old adults at 1 atm. Adding 60-70% N2O reduces the required volatile agent concentration by approximately 50-60%.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care