Adrenaline LA Vasoconstriction Benefits — FRCA Primary MCQ
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Correct answer: D — Vasoconstriction reducing systemic absorption prolonging block duration and reducing peak plasma levels
Adrenaline (typically 1:200000 or 5 μg/mL) causes local vasoconstriction which: slows systemic absorption / prolongs block duration / reduces peak plasma concentration (improving safety margin) / and provides a surgical field with less bleeding. It should be avoided in end-artery areas (digits / penis / nose / ears).
Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care