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Thiopentone Induction Dose 3-5 mg/kg — FRCA Primary MCQ

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EasyPharmacology - Intravenous AnaestheticsThiopentone Induction Dose 3-5 mg/kgFRCA Primary

The dose of thiopentone for induction of anaesthesia is:

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Correct answer: B3-5 mg/kg

Standard induction dose of thiopentone is 3-5 mg/kg IV (typically 4-7 mL of 2.5% solution for a 70 kg adult). The dose should be reduced in: elderly / hypovolaemia / cardiac failure / hepatic disease / and when coadministered with opioids or benzodiazepines. It has the fastest onset of all IV induction agents (one arm-brain circulation time).

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care