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Minto Model Remifentanil — FRCA Primary MCQ

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ModeratePharmacology - Intravenous AnaestheticsMinto Model RemifentanilFRCA Primary

The Minto model is used for TCI of which drug?

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Correct answer: DRemifentanil

The Minto model is a three-compartment PK model for remifentanil TCI. It uses age / sex / and lean body mass as covariates. Remifentanil's rapid ester metabolism gives it a uniquely constant context-sensitive half-time (~3-4 min) making TCI particularly predictable.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care