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Hydrocortisone Stress Dosing — FRCA Primary MCQ

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ModeratePharmacology - AutonomicHydrocortisone Stress DosingFRCA Primary

Hydrocortisone stress dosing in patients with adrenal insufficiency undergoing major surgery is:

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Correct answer: A — 100 mg IV at induction followed by 50 mg 8-hourly for 48-72 hours

For major surgery in patients on long-term steroids (or with adrenal insufficiency): hydrocortisone 100 mg IV at induction then 50 mg 8-hourly for 48-72 hours (or until oral intake resumes). For moderate surgery: 50 mg at induction then 25 mg 8-hourly for 24 hours. For minor surgery: usual oral dose.

Reference: RCoA 2021 Primary FRCA Curriculum