Sevoflurane Fluoride Ions — FRCA Primary MCQ
Instant feedback + full explanation. One question, done properly.
Educational content. Not a substitute for clinical judgement or local policy.
Reveal the answer and explanation
Correct answer: A — Sevoflurane
Sevoflurane is metabolised (3-5%) to produce inorganic fluoride ions. Peak fluoride levels may exceed the 50 μmol/L threshold historically associated with methoxyflurane nephrotoxicity. However clinically significant nephrotoxicity from sevoflurane has not been demonstrated possibly because peak levels are transient compared to the sustained levels seen with methoxyflurane.
Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care