Zona Glomerulosa Aldosterone — FRCA Primary MCQ

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HardPhysiology - Endocrine & MetabolicZona Glomerulosa AldosteroneFRCA Primary

Which hormone is synthesised predominantly in the zona glomerulosa of the adrenal cortex?

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Correct answer: B — Aldosterone from the outer adrenal cortical zona glomerulosa

The best answer is “Aldosterone from the outer adrenal cortical zona glomerulosa”. The zona glomerulosa is the outer cortical layer and synthesises the mineralocorticoid aldosterone. The zona fasciculata produces cortisol and the zona reticularis adrenal androgens; catecholamines are produced in the adrenal medulla. Aldosterone secretion is principally regulated by potassium concentration and the renin–angiotensin system.

Reference: Royal College of Anaesthetists, Primary FRCA Syllabus 2021: https://www.rcoa.ac.uk/sites/default/files/documents/2026-01/Primary-FRCA-Syllabus.pdf