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Glucose PCT Reabsorption — FRCA Primary MCQ

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HardPhysiology - RenalGlucose PCT ReabsorptionFRCA Primary

In a healthy adult, where is filtered glucose reabsorbed almost completely before the urine reaches the loop of Henle?

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Correct answer: C — The proximal tubule through sodium–glucose cotransport systems

The best answer is “The proximal tubule through sodium–glucose cotransport systems”. Filtered glucose is normally reabsorbed almost completely in the proximal tubule via sodium–glucose cotransporters, predominantly SGLT2 early and SGLT1 later. The loop, distal nephron and collecting duct do not provide the normal glucose-reclaiming mechanism. Glycosuria occurs when the filtered load exceeds transport capacity or transport is inhibited.

Reference: Royal College of Anaesthetists, Primary FRCA Syllabus 2021: https://www.rcoa.ac.uk/sites/default/files/documents/2026-01/Primary-FRCA-Syllabus.pdf