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Muscarinic GPCR — FRCA Primary MCQ

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ModeratePharmacology - General PrinciplesMuscarinic GPCRFRCA Primary

Which of the following correctly pairs a receptor type with its signal transduction mechanism?

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Correct answer: C — Muscarinic receptor — G-protein coupled

Muscarinic receptors are G-protein coupled (metabotropic). Nicotinic receptors are ligand-gated ion channels. Insulin receptors are tyrosine kinase-linked. GABA-A receptors are ligand-gated chloride channels. Steroid/thyroid receptors are intracellular nuclear receptors acting as transcription factors.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care