Enzyme Inhibition Rapid Onset — FRCA Primary MCQ
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Correct answer: E — Occurs rapidly within hours to days
Enzyme inhibition occurs rapidly (within hours to days) because it involves direct competition or inactivation of existing enzyme. This contrasts with enzyme induction which takes days to weeks because it requires increased de novo synthesis of enzyme protein. Inhibition can be reversible (competitive) or irreversible (mechanism-based / suicide inhibition).
Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care