Levobupivacaine S-Enantiomer — FRCA Primary MCQ
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Correct answer: A — S(-) enantiomer of bupivacaine
Levobupivacaine is the S(-) enantiomer of bupivacaine. It has similar anaesthetic potency to racemic bupivacaine but reduced cardiotoxicity and CNS toxicity. The R(+) enantiomer is responsible for the greater toxicity of the racemic mixture.
Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care