skip to main content

Isoflurane MAP Reduction — FRCA Primary MCQ

Instant feedback + full explanation. One question, done properly.

ModeratePharmacology - Inhalational AgentsIsoflurane MAP ReductionFRCA Primary

Isoflurane at 1 MAC typically reduces mean arterial pressure by approximately:

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — 25-30%

Isoflurane reduces MAP by approximately 25-30% at 1 MAC primarily through decreased SVR (vasodilation). Heart rate is typically maintained or slightly increased. Cardiac output is relatively preserved compared to halothane which reduces MAP primarily through myocardial depression.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care