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Sevoflurane Desiccated Absorbent — FRCA Primary MCQ

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HardPharmacology - Inhalational AgentsSevoflurane Desiccated AbsorbentFRCA Primary

Sevoflurane interacts with desiccated soda lime to produce:

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Correct answer: DBoth compound A and potentially formaldehyde

Sevoflurane reacting with desiccated CO2 absorbents (particularly barium hydroxide lime) can produce compound A / formaldehyde / carbon monoxide / and methanol. The risk is greatest with desiccated absorbent. Fresh non-desiccated soda lime produces primarily compound A at low levels. Maintaining absorbent hydration is a key safety measure.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care