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Propofol EEG Effects — FRCA Primary MCQ

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HardPharmacology - Intravenous AnaestheticsPropofol EEG EffectsFRCA Primary

Regarding propofol which statement about its effect on the EEG is correct?

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Correct answer: EIt produces burst suppression at high doses but not an isoelectric EEG at clinical doses

Propofol produces dose-dependent EEG changes: initial increase in alpha and beta activity at sedative doses / progressive slowing with theta and delta waves / burst suppression at high doses. True isoelectric EEG occurs only at very high doses. Excitatory movements seen in approximately 10% of patients are NOT true epileptiform activity on EEG.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care