Propofol EEG Effects — FRCA Primary MCQ
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Correct answer: E — It produces burst suppression at high doses but not an isoelectric EEG at clinical doses
Propofol produces dose-dependent EEG changes: initial increase in alpha and beta activity at sedative doses / progressive slowing with theta and delta waves / burst suppression at high doses. True isoelectric EEG occurs only at very high doses. Excitatory movements seen in approximately 10% of patients are NOT true epileptiform activity on EEG.
Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care