Ondansetron 5-HT3 — FRCA Primary MCQ

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EasyPharmacology - AutonomicOndansetron 5-HT3FRCA Primary

Ondansetron acts at which receptor?

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Correct answer: A — 5-HT3 serotonin

Ondansetron is a selective 5-HT3 antagonist acting peripherally on vagal afferents and centrally at the CTZ and NTS. It is effective against chemotherapy-induced and postoperative nausea and vomiting.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care