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EMLA Composition — FRCA Primary MCQ

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EasyPharmacology - AnalgesicsEMLA CompositionFRCA Primary

The EMLA cream is a eutectic mixture of:

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Correct answer: B — Lidocaine 2.5% and prilocaine 2.5%

EMLA = lidocaine 2.5% + prilocaine 2.5%. A eutectic mixture melts at a lower temperature than either constituent alone (~18°C vs lidocaine 68°C and prilocaine 37°C) allowing the LAs to exist as an oil at room temperature for skin penetration.

Reference: Peck Hill Williams 2014 Pharmacology for Anaesthesia and Intensive Care