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JG Cells Renin — FRCA Primary MCQ

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EasyPhysiology - RenalJG Cells ReninFRCA Primary

Juxtaglomerular cells secrete which substance when renal perfusion decreases?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DRenin

JG cells secrete renin in response to: decreased perfusion pressure / decreased NaCl at macula densa / increased sympathetic activity (beta-1). Renin converts angiotensinogen to angiotensin I which is then converted to angiotensin II by ACE.

Reference: Power Kam 2018 Principles of Physiology for the Anaesthetist