Haldane Effect Definition — FRCA Primary MCQ
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Correct answer: A — The effect of oxygenation on CO2 carriage by haemoglobin
The Haldane effect describes how deoxygenated Hb carries more CO2 than oxygenated Hb. In tissues deoxygenation facilitates CO2 loading. In lungs oxygenation facilitates CO2 unloading. It accounts for the majority of CO2 exchange and complements the Bohr effect.
Reference: Power Kam 2018 Principles of Physiology for the Anaesthetist