Renin Secretion JG Cells — FRCA Primary MCQ
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Correct answer: C — Renin released from juxtaglomerular granular cells
The best answer is “Renin released from juxtaglomerular granular cells”. Juxtaglomerular granular cells in the afferent arteriole release renin in response to reduced perfusion pressure, reduced macula-densa sodium chloride delivery and beta-1 sympathetic stimulation. Renin cleaves hepatic angiotensinogen to angiotensin I. Aldosterone, angiotensin II and erythropoietin arise from different tissues or steps in the pathway.
Reference: Royal College of Anaesthetists, Primary FRCA Syllabus 2021: https://www.rcoa.ac.uk/sites/default/files/documents/2026-01/Primary-FRCA-Syllabus.pdf