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Desflurane Vaporiser — FRCA Primary MCQ

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ModeratePhysics & Clinical MeasurementDesflurane VaporiserFRCA Primary

Which physicochemical property and corresponding design feature best explain why a Tec 6 desflurane vaporiser differs from a conventional variable-bypass vaporiser?

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Correct answer: AA boiling point close to room temperature and high saturated vapour pressure require a heated, thermostatically controlled, pressurised vapour circuit

Desflurane boils at 22.8°C and therefore has a saturated vapour pressure close to atmospheric pressure at ordinary theatre temperatures. Output from a conventional variable-bypass vaporiser would consequently be difficult to control, with a risk of boiling and marked temperature-dependent variation. The Tec 6 instead heats desflurane to a controlled temperature and generates pressurised vapour in a separate circuit, which is metered and blended with the fresh gas. Option D reverses desflurane’s physical properties. Option B incorrectly describes it as poorly volatile. A wick and temperature-compensated bypass chamber are features of conventional agent-specific vaporisers, making D incorrect. Desflurane can be delivered with oxygen, air or oxygen–nitrous oxide mixtures, so nitrous oxide is not obligatory.

Reference: Andrews JJ, Johnston RV. The new Tec 6 desflurane vaporizer. Anesthesia & Analgesia. 1993;76(6):1338–1341. https://pubmed.ncbi.nlm.nih.gov/8498675/