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Renal Autoregulation — FRCA Primary MCQ

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HardPhysiology - RenalRenal AutoregulationFRCA Primary

In a healthy normotensive adult, renal autoregulation usually maintains relatively stable renal blood flow and GFR over which mean arterial pressure range?

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Correct answer: B80–180 mmHg, the conventional healthy-adult autoregulatory range

The best answer is “80–180 mmHg, the conventional healthy-adult autoregulatory range”. Renal blood flow and GFR are conventionally described as relatively constant between mean arterial pressures of about 80 and 180 mmHg in a healthy person. Myogenic afferent-arteriolar responses and tubuloglomerular feedback mediate this. Chronic hypertension, sepsis, drugs and renal disease can shift or impair the autoregulatory range.

Reference: Royal College of Anaesthetists, Primary FRCA Syllabus 2021: https://www.rcoa.ac.uk/sites/default/files/documents/2026-01/Primary-FRCA-Syllabus.pdf