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Trigeminal Neuralgia Second-Line — FRCA Final MCQ

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HardPain MedicineTrigeminal Neuralgia Second-LineFRCA Final

Trigeminal neuralgia V2 distribution: carbamazepine and oxcarbazepine failed (hyponatraemia). Next pharmacological treatment?

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Correct answer: CLamotrigine

TN: carbamazepine first-line (NICE specifically for TN). Oxcarbazepine alternative. Both failed/hyponatraemia: lamotrigine has best evidence from small RCTs. Refer for neurosurgical assessment after 2 failed drugs.

Reference: NICE – 2023 – CG173; AAN – 2023 – TN guideline