Oral SC Morphine Conversion — FRCA Final MCQ

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ModeratePain MedicineOral SC Morphine ConversionFRCA Final

Oral morphine MR 60 mg BD needs conversion to SC infusion (can't swallow). Correct 24h SC dose?

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Correct answer: E — 60 mg

Oral:SC morphine ratio = 2:1. Daily oral = 120 mg. SC 24h = 120/2 = 60 mg via CSCI. Breakthrough SC = 1/6 of 24h dose (10 mg PRN). Some guidelines use 3:1 (40 mg/24h). Use local protocol and monitor.

Reference: BNF – 2025 – Palliative care opioid conversion