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Neuropathic Pain NICE Stepwise — FRCA Final MCQ

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ModeratePain MedicineNeuropathic Pain NICE StepwiseFRCA Final

Diabetic neuropathy: amitriptyline (anticholinergic side effects) and pregabalin (dizziness/weight gain) failed. NICE CG173 next step?

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Correct answer: CDuloxetine

NICE CG173 first-line: amitriptyline, duloxetine, gabapentin, pregabalin. After 2 failures, switch to another first-line. Duloxetine (SNRI) has strong diabetic neuropathy evidence. Tramadol third-line. Carbamazepine specifically for trigeminal neuralgia.

Reference: NICE – 2023 – CG173 Neuropathic pain