Codeine Morphine Conversion — FRCA Final MCQ

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EasyPain MedicineCodeine Morphine ConversionFRCA Final

Codeine 30 mg QDS for 2 years. Convert to oral morphine (10:1 ratio). 24h oral morphine dose?

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Correct answer: A — 12 mg

Codeine:morphine ~10:1. Daily codeine = 120 mg. Oral morphine = 12 mg/24h. Start at 50-75% for incomplete cross-tolerance and titrate. BNF/FPM emphasise individual assessment over formulaic conversion.

Reference: BNF – 2025 – Opioid equivalence; FPM – 2023