Colistin Nephrotoxicity — FRCA Final MCQ

Instant feedback + full explanation. One question, done properly.

HardIntensive Care MedicineColistin NephrotoxicityFRCA Final

MDR Acinetobacter pneumonia: only colistin-sensitive. Most significant side effect to monitor?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Nephrotoxicity

IV colistin: nephrotoxicity in up to 50% of patients. Direct renal tubular damage. Dose-limiting toxicity. TDM and renal monitoring essential. Neurotoxicity (paraesthesia, dizziness) occurs but less common than nephrotoxicity.

Reference: IDSA – 2022 – Resistant Gram-negative infections; BSAC – 2023