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HIT Type II Management — FRCA Final MCQ

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ModerateIntensive Care MedicineHIT Type II ManagementFRCA Final

Platelets 180→45, new DVT on prophylactic LMWH. 4T score 7. Diagnosis and management?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — HIT — stop all heparin, start argatroban

4T score 7 (high probability) + thrombocytopenia + new thrombosis on heparin = HIT type II. Stop ALL heparin (including flushes, coated lines). Start argatroban (hepatic metabolism, short half-life). Anti-PF4 antibodies. NO warfarin until platelets recover.

Reference: BSH – 2023 – HIT diagnosis and management