Massive Transfusion 1:1:1 — FRCA Final MCQ

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EasyTrauma & Emergency AnaesthesiaMassive Transfusion 1:1:1FRCA Final

Massive transfusion for traumatic bilateral above-knee amputations. Initial blood product ratio?

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Correct answer: A — 1:1:1 PRBC:FFP:platelets

PROPPR trial: 1:1:1 ratio reduces death from exsanguination. Mimics whole blood composition. TXA 1g IV within 3h (CRASH-2). Minimise crystalloid. Activate MTP early. Damage control: permissive hypotension (SBP 80-90), avoid hypothermia.

Reference: NICE – 2023 – NG39 Major trauma; PROPPR – 2015