Controlled Hypocapnia Target — FRCA Final MCQ
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Correct answer: B — 4.0-4.5 kPa
Mild hyperventilation targeting PaCO2 4.0-4.5 kPa (30-34 mmHg). Each 1 kPa change alters CBF ~15-20%. Aggressive hyperventilation (<3.5 kPa) causes cerebral ischaemia. BTF: avoid PaCO2 <25 mmHg (3.3 kPa) routinely.
Reference: BTF – 2016 – Hyperventilation guidelines