Acute Brain Herniation Management — FRCA Final MCQ
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Correct answer: B — Hypertonic saline 2.7% 3 mL/kg
Hypertonic saline provides fastest ICP reduction (onset 5-10 min) via immediate osmotic gradient. Mannitol effective but slower (15-20 min). Hypertonic saline also expands intravascular volume. Dexamethasone works only for vasogenic oedema (hours onset).
Reference: SBNS/RCOA – 2023 – Neuroanaesthesia: raised ICP management