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Phenylephrine Reflex Bradycardia — FRCA Final MCQ

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ModerateObstetric AnaesthesiaPhenylephrine Reflex BradycardiaFRCA Final

Phenylephrine infusion during spinal for CS causes bradycardia. Main mechanism?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EBaroreceptor-mediated reflex bradycardia

Phenylephrine (pure alpha-1 agonist) increases SVR/MAP → activates carotid baroreceptor reflex → increased vagal tone → reflex bradycardia. Physiological response, not direct cardiac effect. With spinal sympathetic blockade, the reflex can be pronounced.

Reference: BJA Education – 2023 – Vasopressors in obstetric anaesthesia